Biopharm High Capacity PVDF Cartridge Filters0 pages
BPVWL Cartridge Filters
High Capacity PVDF Membrane
Applications
SVPs
WFI Water
LVPs
Serum
Vaccines
Plasma Products
Dimensions
Length
5 to 40 in. (12.7 to 101.6 cm) nominal
Outside Diameter
2.75 in. (7.0 cm) nominal
Integrity Test Information
Representative samples from each manufacturing lot are tested
for integrity to ensure consistent performance.
Biopharmaceutical grade PVWL filters are made using hydrophilic
polyvinylidene fluoride (PVDF) membrane. The proprietary
membrane casting process creates a thick membrane with
excellent retention characteristics and flow rates and low protein
binding. BPVWL cartridges are used for a wide range of critical
applications in the biopharmaceutical production.
Applications include bioburden reduction in buffers and media,
water for injection (WFI), solvents, alcohols and other liquids. Our
filters provide high efficiency, validatable performance protecting
sterilizing grade filters.
PVDF is particularly suited for the filtration of products containing
elements that can adsorb to the media, such as preservatives and
proteins. The very low binding nature of PVDF makes it a good
choice for filtration of valuable protein solutions such as vaccines,
plasma products, MAb products, other biopharmaceuticals as
well as products that contain low amounts of preservatives.
Construction Materials
Filtration Media
High Capacity Polyvinylidene
Fluoride (PVDF) Membrane
Media Support
Polypropylene
End Caps
Polypropylene
Center Core
Polypropylene
Outer Support Cage
Polypropylene
Sealing Method
Thermal Bonding
O-rings
Buna, Viton® (or FKM), EP, Silicone,
FEP Encapsulated Silicone, FEP
Encapsulated Viton (or FKM)
Maximum Operating Parameters
Differential Pressure
•t Forward
50 psid (3.4 bard) at 20 °C (68 °F)
•t Reverse
40 psid (2.7 bard) at 20 °C (68 °F)
Operating Temperature
Recommended
Changeout Pressure
82 °C (180 °F) at 10 psid
(0.69 bard) in water
35 psid (2.4 bard)
Sanitization/Sterilization
Filtered Hot Water
90 °C (194 °F), 30 minutes, multiple
cycles, max 3 psid forward flow
Autoclave
121 °C (250 °F), 30 min, multiple cycles
In-line Steam
135 °C (275 °F), 30 min, multiple cycles
For all elevated temperature procedures above, a stainless steel
support ring is required.
Chemical Sanitization
Performed using industry standard concentrations of hydrogen
peroxide, paracetic acid, sodium hypochlorite, and other
selected chemicals.
Total Performance
Critical Process Filtration, Inc. is a vertically integrated
manufacturer of filtration products to industries in which
filtration is considered a critical part of the manufacturing
process. We supply a complete line of products and services to
help you cost effectively satisfy all your filtration requirements
from a single source.
Biopharmaceutical Grade
Buffers and Feedstocks
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