Autogizer20 pages

TOMTECQ

Life Sciences

AutogizerS

Product Brief

The Autogizer2™ is a fully automated tissue homogenization system.

With its five variable speed cutters, it can process up to 19 unique tissue

groups per run for a total of 95 samples. The Tomtec manufacturing team

can also design and deliver a sample containment rack to your unique

specifications. The Autogizer2 is shipped with five (5) variable-speed,

high torque, low noise Omni International® brushless cutter motors,

which can accommodate 7 mm (standard) or 10 mm cutters. The

Autogizer2 runs under an imbedded image of Windows driving an

intuitive graphical user interface for setting motor speed, duration, mixer

depth and blade cleaning cycle between processed tissue groups.

At-a-G lance

Walk-away operation - Programmable

Windows based with powerful

Graphical User Interface

Fast and Efficient - Homogenize 5

samples at a time, four cutter tips

supported

Integrated cutter cleaning - Three

aqueous, organic, aqueous

(ultrasonic) cleaning tanks

Production ready - Process up to 95

samples per run, optional custom-built

sample-racks

Reliable - Results are absolutely

consistent and repeatable Ideal for

PK studies

The AutogizerS features-benefits

The powerful Windows graphical user interface provides an advanced

GUI for supporting a multi-step tissue homogenization process

controlling five (5) reliable Omni International® brushless cutter motors.

The cutters run in lock-step and deliver controlled torque and RPM at a

low noise level. The Autogizer2 can be programmed to walk a line of

samples and deliver a unique homogenization protocol per line (five vials

per line). The cutters functions are:

1) RPM delivered over time, this can be variable with pauses;

2) The number of total cycles delivered into the tissue;

3) Total time on station and

4) Up/down travel limits and rate of oscillation.

For work-flows where sample temperature is a concern or when cryogenic homogenization is required, the sample rack

can be fitted with a load & go ice-bath or an automated coolant system which can be monitored under program control.

As your Homogenization program progresses (between each lines of vials processed), the cutters can be programmed

to pass through a (1) bulk wash, (2) organic rinse and/or (3) ultrasonic wash station. An optional wash & waste

collection cart is available for waste containment.

Example Applications

The Tomtec Autogizer2 can accommodate a wide range of lab applications such as tissue homogenization, emulsions

and suspensions, cell disruption, protein extraction and various classes of medical laboratory research. Our cutting tips

are designed to smoothly shear samples with minimal cavitation, minimizing unwanted heating and tissue disruption.

Cell lyses

The Homogenized is designed to bring your biological tissue sample to a state where all fractions are equal in

composition and makeup. The flexibility and control delivered with the autogizer2 ensures that your post process cell

lyses and/or molecular extraction are absolutely consistent and repeatable. This is achieved experimentally by

determining optimal spin-up/spin-down rates, mixing protocols, temperature and wash cycle; then programming them

into the Autogizer2, allowing you to achieve optimal, repeatable results.

Tomtec Life Science

1000 Sherman Ave., Hamden, Connecticut 06514

+1.877.866.8323