Thermo Scientific Orbitrap Fusion Lumos Tribrid Mass Spectrometer0 pages

MASS SPECTROMETRY

Breakthrough Gains for Quantitative Biology
Sensitivity Transformed

Product Specif ications

Thermo Scientific
Orbitrap Fusion Lumos
Tribrid Mass Spectrometer

The Thermo Scientific™ Orbitrap Fusion™ Lumos™
Tribrid™ mass spectrometer is the industry-leading
high-performance mass spectrometer with enhanced
sensitivity facilitated by a new High Capacity Transfer
Tube, Electrodynamic Ion Funnel, Advanced Quadrupole
Technology, Advanced Vacuum Technology, and ETD HD.

Novel Orbitrap Fusion Lumos MS
Features
• ovel high-sensitivity API interface
N
combines a High Capacity Transfer
Tube and an Electrodynamic Ion Funnel
for increased ion flux and lower limits
of detection
• dvanced Active Beam Guide (AABG)
A
prevents neutrals and high velocity
clusters from entering the resolving
quadrupole
• dvanced Quadrupole Technology
A
(AQT) combines high selectivity and
efficiency of transfer for the selected
ions symmetrically across the
isolation window
• dvanced Vacuum Technology
A
for improved transmission of high
molecular weight ions to the
Orbitrap analyzer
• ovel ETD HD—high dynamic range
N
ETD providing significantly increased
fragment ion coverage

Established Tribrid Features
• ribrid architecture includes quadrupole
T
mass filter, linear ion trap and Orbitrap
mass analyzers
• ltra high-field Orbitrap analyzer for
U
ultra-high resolution and the fastest
Orbitrap acquisition rates
• esolving power up to 500,000 FWHM,
R
with isotopic fidelity up to 240,000 FWHM
at m/z 200
• arge surface area ion trap detector for
L
significantly improved robustness and
life span
• ull parallelization of MS and MS n analyses
F
with intelligent ADAPT ™ (All Dynamically
Available Parallelizable Time) technology
• ynchronous Precursor Selection (SPS) for
S
MS and MS n experiments
• ultiple fragmentation techniques: CID,
M
HCD and optional ETD and EThcD available
at any stage of MS n with detection in either
the Orbitrap or linear ion trap detector
• Unique Tribrid architecture allows for

high acquisition rates in Orbitrap and
linear ion trap analyzers and maximum
flexibility for dissociation and detection
of fragment ions
• ompact ETD ion source based on
C
Townsend discharge with extremely stable
anion flux for improved usability and
reagent longevity
• cquisition rates of up to 20 Hz for both
A
Orbitrap and linear ion trap MS n analyses
• niversal Method provides maximal
U
peptide identifications without method
optimization for samples of unknown
concentration, reducing sample and
instrument time requirements for routine
peptide identification experiments
• ntuitive and flexible drag-and-drop user
I
interface simplifies method development
and enables unique and complex workflows