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Brochure autoflex III & autoflex III TOF/TOF0 pages
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CLINPROT solution package provides researchers with comprehensive tools for biomarker research: Profiling, tissue imaging and marker identification | ||||||||||||||||||||||
Technical specifications Cutting-edge technology smartbeam lasertechnology: Top performance with any chosen matrix, outperforming the YAG-laser. Օ PAN: Highest mass resolution at every mass from 700 - 5,000 Da. HPC: High Precision Calibration for highest mass accuracy. Analytical performance Օ smartbeam laserwith adjustable repetition rate from 1-200 Hz. Excellent resolution > 1,000 and brilliant mass accuracy of<100 ppm in linear mode for protein samples; a prerequisite for MALDI Imaging and Biomarker Profiling workflows. Օ Impressive resolution > 10,000 over extended mass range window (> 3,500 mass units) using Bruker Daltonics' unique PAN (panoramic) technology. ٕ Remarkable mass accuracy of<5 ppm for peptide mass range in reflectron mode. Striking sensitivity in attomole range with high signal-to-noise ratio in TOF/TOF mode. Compass software suite Օ flexControl for quick and easy instrument control. flexAnalysis for automatic and interactive data analysis. Optional packages: Օ BioTools, the cutting edge software for protein analysis. ٕ WARP-LC, the LC-MALDI and protein quantitation software. ٕ ClinProTools, the software for biomarkervisualization and discovery. ٕ flexlmaging, the software for MALDI imaging applications. ٕ ProteinScape database system for proteomics project management. ٕ CompassSecurityPack,21CFRpart11 compliance. | ||||||||||||||||||||||
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Identification A (MS/MS) """"iifUfiT | ||||||||||||||||||||||
autoflex III smartbeam | ||||||||||||||||||||||
Cutting edge MALDI-TOF/TOF systems | ||||||||||||||||||||||
Be a part of Intelligent Teamwork | ||||||||||||||||||||||
Maximizing data verification and understanding of scientific problems is accomplished by tight integration of analytical systems. Statistical data from the autoflexIII smartbeam, achieved with the CLINPROT solution package, can easily be merged with molecular images in the MALDI Molecular Imager system, thus allowing the monitoring of the tissue distributions of peptide and protein biomarkers. Peak Profile Classification + MALDI Imaging = Class Imaging | ||||||||||||||||||||||
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Support features Extended self diagnostics. 䕕 Remote on-line service capability. Supplementary IQ/OQ/PV procedures available. Օ Custom-tailored maintenance contracts available. | ||||||||||||||||||||||
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The autoflex smartbeam seamlessly integrates | into | |||||||||||||||||||||
Bruker Daltonics' system solutions: MALDI Molecular Imagerՙ - Mass Spectrometry-Based Imaging CLINPROTՙ - Mass Spectrometry-Based BiomarkerAnalysis PROTEINEER-LCՙ - LC-based Proteomics Suite PROTEINEERՙ - 2D Gel-based Proteomics Suite For research use only. Not for diagnostic procedures. | ||||||||||||||||||||||
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Class Imaging enhances Mass Imaging - the principle: Peak profiles (B) of defined regions of interest (ROI, A) in a tissue slice are used to calculate a classification model (C). The resulting classes (D) are then used to stain the tissue slice class-specifically (E): Detect the spatial distribution of statistically relevant markers! Example: Sagittal section of the cerebellum of the rat brain. (A) HA stain; (B, C) ClinProTools analysis; (D, E) MALDI Molecular Imager analysis | ||||||||||||||||||||||
www.bdal.de www.bdal.com | ||||||||||||||||||||||
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Bruker Daltonik GmbH Bremen ■ Germany Phone +49(421)22 05-0 Fax +49(421)22 05-104 E-Mail sales@bdal.de | Bruker Daltonics Inc. Billerica, MA ■ USA Phone +1 (978)663-3660 Fax +1(978)667-5993 E-Mail ms-sales@bdal.com | |||||||||||||||||||||
BRUKER DALTONICS | ||||||||||||||||||||||
DALT0NC5 Enabling Life Science Tools Based on Mass SpectrometryΙ | ||||||||||||||||||||||
See our website for worldwide sales and service contacts. |